WB analysis of HeLa, MEF cells, and rat brain tissue lysate using GTX48589 OPA1 antibody. Dilution : 1 microg/ml
WB analysis of HeLa, MEF cells, and rat brain tissue lysate using GTX48589 OPA1 antibody. Dilution : 1 microg/ml
OPA1 antibody
GTX48589
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityChicken, Human, Mouse, Porcine, Primate, Rat, Zebra Fish
TargetOPA1
Overview
- SupplierGeneTex
- Product NameOPA1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 2 microg/ml. IHC-P: 2.5 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4976
- Target nameOPA1
- Target descriptionOPA1 mitochondrial dynamin like GTPase
- Target synonymsBERHS; dynamin-like 120 kDa protein, mitochondrial; dynamin-like guanosine triphosphatase; largeG; MGM1; mitochondrial dynamin-like GTPase; MTDPS14; NPG; NTG; optic atrophy 1 (autosomal dominant); optic atrophy protein 1
- HostRabbit
- IsotypeIgG
- Protein IDO60313
- Protein NameDynamin-like 120 kDa protein, mitochondrial
- Scientific DescriptionThis gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityChicken, Human, Mouse, Porcine, Primate, Rat, Zebra Fish
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis. Chung KP et al., 2019 Jul 29, Nat CommunRead more
- Beclin-1 regulates cigarette smoke-induced kidney injury in a murine model of chronic obstructive pulmonary disease. Pabon MA et al., 2018 Sep 20, JCI InsightRead more
- The Truncated C-terminal Fragment of Mutant ATXN3 Disrupts Mitochondria Dynamics in Spinocerebellar Ataxia Type 3 Models. Hsu JY et al., 2017, Front Mol NeurosciRead more
- Dengue virus induces mitochondrial elongation through impairment of Drp1-triggered mitochondrial fission. Barbier V et al., 2017 Jan, VirologyRead more
- Metabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells. Cheng CT et al., 2016 Sep 1, Cancer ResRead more
- Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins. Yu CY et al., 2015 Dec, PLoS PathogRead more
- Cigarette smoke extract affects mitochondrial function in alveolar epithelial cells. Ballweg K et al., 2014 Dec 1, Am J Physiol Lung Cell Mol PhysiolRead more
- Impaired translocation and activation of mitochondrial Akt1 mitigated mitochondrial oxidative phosphorylation Complex V activity in diabetic myocardium. Yang JY et al., 2013 Jun, J Mol Cell CardiolRead more