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ProductsBack/p27 Kip1 antibody
The data was published in the journal Mol Cell Endocrinol in 2013.PMID: 23791816
The data was published in the journal Mol Cell Endocrinol in 2013.PMID: 23791816
The data was published in the journal Mol Cell Endocrinol in 2013.PMID: 23791816

p27 Kip1 antibody

GTX27961
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
DownloadDatasheet
Product group Antibodies
TargetCDKN1B
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Overview

  • Supplier
    GeneTex
  • Product Name
    p27 Kip1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1027
  • Target name
    CDKN1B
  • Target description
    cyclin dependent kinase inhibitor 1B
  • Target synonyms
    CDKN4; cyclin-dependent kinase inhibitor 1B; cyclin-dependent kinase inhibitor 1B (p27, Kip1); KIP1; MEN1B; MEN4; P27KIP1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP46527
  • Protein Name
    Cyclin-dependent kinase inhibitor 1B
  • Scientific Description
    This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Design of ion channel blocking, toxin-like Kunitz inhibitor peptides from the tapeworm, Echinococcus granulosus, with potential anti-cancer activity.
    Read more
  • Exposure to chemical cocktails before or after conception--- the effect of timing on ovarian development. Bellingham M et al., 2013 Aug 25, Mol Cell Endocrinol
    Read more
  • Progesterone receptor is involved in 2,3,7,8-tetrachlorodibenzo-p-dioxin-stimulated breast cancer cells proliferation. Chen YJ et al., 2012 Jun 28, Cancer Lett
    Read more

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