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Immunohistochemical staining of a formalin-fixed, paraffin-embedded placental tissue with GTX60972
Immunohistochemical staining of a formalin-fixed, paraffin-embedded placental tissue with GTX60972
Immunohistochemical staining of a formalin-fixed, paraffin-embedded placental tissue with GTX60972

PAPP A antibody [PAPP A 1-1]

Research Use Only
GTX60972
GeneTex
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetPAPPA
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    PAPP A antibody [PAPP A 1-1]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody is specific for native human PAPP-A
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    PAPP A 1-1
  • Conjugate
    Unconjugated
  • Gene ID5069
  • Target name
    PAPPA
  • Target description
    pappalysin 1
  • Target synonyms
    ASBABP2; aspecific BCL2 ARE-binding protein 2; differentially placenta 1 expressed protein; DIPLA1; IGFBP-4ase; IGF-dependent IGFBP-4 protease; insulin-like growth factor-dependent IGF binding protein-4 protease; PAPA; PAPP-A; PAPPA1; pappalysin-1; pregnancy-associated plasma protein A, pappalysin 1
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers. [provided by RefSeq, Aug 2017]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203