![IHC-P analysis of rat spleen tissue section using GTX09509 PARP antibody [GT1176]. Dlution : 1:100 IHC-P analysis of rat spleen tissue section using GTX09509 PARP antibody [GT1176]. Dlution : 1:100](https://www.genetex.com/upload/website/prouct_img/normal/GTX09509/GTX09509_20191101_AP_003_119_w_23053123_115.webp)
IHC-P analysis of rat spleen tissue section using GTX09509 PARP antibody [GT1176]. Dlution : 1:100
PARP antibody [GT1176]
GTX09509
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPARP1
Overview
- SupplierGeneTex
- Product NamePARP antibody [GT1176]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT1176
- ConjugateUnconjugated
- Gene ID142
- Target namePARP1
- Target descriptionpoly(ADP-ribose) polymerase 1
- Target synonymsADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PARS, PPOL, Poly-PARP, pADPRT-1, poly [ADP-ribose] polymerase 1, ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase), ADP-ribosyltransferase NAD(+), ADP-ribosyltransferase diphtheria toxin-like 1, DNA ADP-ribosyltransferase PARP1, NAD(+) ADP-ribosyltransferase 1, poly (ADP-ribose) polymerase family, member 1, poly(ADP-ribose) synthetase, poly(ADP-ribosyl)transferase, poly[ADP-ribose] synthase 1, protein poly-ADP-ribosyltransferase PARP1
- HostRabbit
- IsotypeIgG
- Protein IDP09874
- Protein NamePoly [ADP-ribose] polymerase 1
- Scientific DescriptionThis gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
![IHC-P analysis of hmuan appendix tissue section using GTX09509 PARP antibody [GT1176]. Dlution : 1:100 IHC-P analysis of hmuan appendix tissue section using GTX09509 PARP antibody [GT1176]. Dlution : 1:100](https://www.genetex.com/upload/website/prouct_img/normal/GTX09509/GTX09509_20191101_AP_003_120_w_23053123_297.webp)
![IHC-P analysis of mouse spleen tissue section using GTX09509 PARP antibody [GT1176]. Dlution : 1:100 IHC-P analysis of mouse spleen tissue section using GTX09509 PARP antibody [GT1176]. Dlution : 1:100](https://www.genetex.com/upload/website/prouct_img/normal/GTX09509/GTX09509_20191101_AP_003_121_w_23053123_210.webp)
![WB analysis of Wild-type (WT) and PARP knockout (KO) HeLa cell extracts using GTX09509 PARP antibody [GT1176]. Dilution : 1:1000 Loading : 25microg WB analysis of Wild-type (WT) and PARP knockout (KO) HeLa cell extracts using GTX09509 PARP antibody [GT1176]. Dilution : 1:1000 Loading : 25microg](https://www.genetex.com/upload/website/prouct_img/normal/GTX09509/GTX09509_20200327_WB_1_w_23053123_134.webp)
![WB analysis of Jurkat cells were treated with/without Staurosporine (1microM) at RT for 3 hrs using GTX09509 PARP antibody [GT1176]. Dilution : 1:1000 Loading : 25microg WB analysis of Jurkat cells were treated with/without Staurosporine (1microM) at RT for 3 hrs using GTX09509 PARP antibody [GT1176]. Dilution : 1:1000 Loading : 25microg](https://www.genetex.com/upload/website/prouct_img/normal/GTX09509/GTX09509_20200327_WB_2_w_23053123_561.webp)
![Untreated (-) and treated (+) HeLa whole cell extracts (30 microg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PARP antibody [GT1176] (GTX09509) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Untreated (-) and treated (+) HeLa whole cell extracts (30 microg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PARP antibody [GT1176] (GTX09509) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX09509/GTX09509_40000000075_20200306_WB_treatment_Cisplatin_w_23053123_130.webp)
![Various whole cell extracts (30 microg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PARP antibody [GT1176] (GTX09509) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program. Various whole cell extracts (30 microg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PARP antibody [GT1176] (GTX09509) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.](https://www.genetex.com/upload/website/prouct_img/normal/GTX09509/GTX09509_40000000075_20200306_WB_watermark_TPM_w_23053123_252.webp)



![FACS analysis of Jurkat cells using GTX83005 PARP antibody [7A10]. Green : PARP Purple : negative control](https://www.genetex.com/upload/website/prouct_img/normal/GTX83005/GTX83005_20170912_FACS_w_23061322_421.webp)

