PCNA antibody [131-11912(19A2-17)]

GeneTex

PCNA antibody [131-11912(19A2-17)]

9

PCNA (Proliferating Cell Nuclear Antigen), formerly called Cyclin, is a 36 kD proliferation associated antigen.

ELISA

Research Use Only

Monoclonal

131-11912(19A2-17)

Unconjugated

PCNA

proliferating cell nuclear antigen

ATLD2; cyclin; DNA polymerase delta auxiliary protein; proliferating cell nuclear antigen

Mouse

IgM

Proliferating cell nuclear antigen

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203