WB analysis of purified PD-L1 recombinant protein using GTX14145 PD-L1 antibody [10F.9G2]. Lane 1 : 0.1 ug reduced purified mouse PD-L1 with histidine tag at C-terminuse Lane 2 : 0.05 ug reduced purified mousePD-L1 with histidine tag at C-terminus Dilution : 8 ug/ml
WB analysis of purified PD-L1 recombinant protein using GTX14145 PD-L1 antibody [10F.9G2]. Lane 1 : 0.1 ug reduced purified mouse PD-L1 with histidine tag at C-terminuse Lane 2 : 0.05 ug reduced purified mousePD-L1 with histidine tag at C-terminus Dilution : 8 ug/ml
PD-L1 antibody [10F.9G2]
GTX14145
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
Product group Antibodies
ReactivityMouse
TargetCd274
Overview
- SupplierGeneTex
- Product NamePD-L1 antibody [10F.9G2]
- Delivery Days Customer9
- Application Supplier Note*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID10F.9G2
- ConjugateUnconjugated
- Gene ID60533
- Target nameCd274
- Target descriptionCD274 antigen
- Target synonymsA530045L16Rik; B7 homolog 1; B7h1; PD-; PDCD1 ligand 1; Pdcd1l; Pdcd1l1; Pdcd1lg1; Pdl1; programmed cell death 1 ligand 1
- HostRat
- IsotypeIgG2b
- Protein IDQ9EP73
- Protein NameProgrammed cell death 1 ligand 1
- Scientific DescriptionThe protein encoded by this gene is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Mice deficient for this gene display a variety of phenotypes including decreased allogeneic fetal survival rates and severe experimental autoimmune encephalomyelitis. [provided by RefSeq, Sep 2015]
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203