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ProductsBack/PF-4618433 [1166393-85-6]
Chemical Structure
Chemical Structure
Chemical Structure

PF-4618433 [1166393-85-6]

SYN-1163
SYNkinase
CAS Number1166393-85-6
Product group Chemicals
Estimated Purity>95%
Molecular Weight445.5
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Overview

  • Supplier
    SYNkinase
  • Product Name
    PF-4618433 [1166393-85-6]
  • Delivery Days Customer
    10
  • CAS Number
    1166393-85-6
  • Estimated Purity
    >95%
  • Molecular Formula
    C24H27N7O2
  • Molecular Weight
    445.5
  • Scientific Description
    Chemical. CAS: 1166393-85-6. Formula: C24H27N7O2. MW: 445.5. Potent and selective PYK2 inhibitor. PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796. In the functional osteogenesis assays, cultures treated with increasing concentrations of PF-4618433 starting at day 1 and maintained throughout showed a dose-dependent increases in both alkaline phosphatase activity and mineralization. - Potent and selective PYK2 inhibitor. PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796. In the functional osteogenesis assays, cultures treated with increasing concentrations of PF-4618433 starting at day 1 and maintained throughout showed a dose-dependent increases in both alkaline phosphatase activity and mineralization.
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    51202000