PGK1 + PGK2 antibody [HL1775]

GeneTex

PGK1 + PGK2 antibody [HL1775]

9

WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

HL1775

1 mg/ml

Unconjugated

PGK1

phosphoglycerate kinase 1

cell migration-inducing gene 10 protein; epididymis secretory sperm binding protein Li 68p; HEL-S-68p; MIG10; PGKA; phosphoglycerate kinase 1; primer recognition protein 2; PRP 2

Rabbit

IgG

Phosphoglycerate kinase 1

The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]

Human, Mouse, Rat, Zebra Fish

-20°C or -80°C,2°C to 8°C

12352203