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PI3 kinase p85 (phospho Tyr467)/p55 (phospho Tyr199) antibody

GTX132597
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPIK3R1
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Overview

  • Supplier
    GeneTex
  • Product Name
    PI3 kinase p85 (phospho Tyr467)/p55 (phospho Tyr199) antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.02 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID5295
  • Target name
    PIK3R1
  • Target description
    phosphoinositide-3-kinase regulatory subunit 1
  • Target synonyms
    AGM7; GRB1; IMD36; p85; p85-ALPHA; phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; phosphatidylinositol 3-kinase regulatory subunit alpha; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); phosphatidylinositol 3-kinase-associated p-85 alpha; phosphoinositide-3-kinase regulatory subunit alpha; phosphoinositide-3-kinase, regulatory subunit 1 (alpha); PI3K regulatory subunit alpha; PI3-kinase subunit p85-alpha; ptdIns-3-kinase regulatory subunit alpha
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP27986
  • Protein Name
    Phosphatidylinositol 3-kinase regulatory subunit alpha
  • Scientific Description
    Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • PI3K/Akt signalling pathway-associated long noncoding RNA signature predicts the prognosis of laryngeal cancer patients.
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  • BFNB Enhances Hair Growth in C57BL/6 Mice through the Induction of EGF and FGF7 Factors and the PI3K-AKT-beta-Catenin Pathway.
    Read more
  • CD36 regulates diurnal glucose metabolism and hepatic clock to maintain glucose homeostasis in mice.
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  • DDTC Suppresses Ovarian Cancer Development via the PI3K/AKT/mTOR Signaling Pathway.
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  • Systemic Deficiency of PTEN Accelerates Breast Cancer Growth and Metastasis. Chen J et al., 2022, Front Oncol
    Read more
  • Effect of Neurorepair for Motor Functional Recovery Enhanced by Total Saponins From Trillium tschonoskii Maxim. Treatment in a Rat Model of Focal Ischemia. Yang L et al., 2021, Front Pharmacol
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  • Rapamycin attenuates PLA2R activation-mediated podocyte apoptosis via the PI3K/AKT/mTOR pathway. Chiou TT et al., 2021 Dec, Biomed Pharmacother
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  • The Mechanism of Xiaoyao San in the Treatment of Ovarian Cancer by Network Pharmacology and the Effect of Stigmasterol on the PI3K/Akt Pathway. Li M et al., 2021, Dis Markers
    Read more
  • Downregulation of miR-483-5p inhibits TGF-beta1-induced EMT by targeting RhoGDI1 in pulmonary fibrosis. Huang G et al., 2021 Jul, Mol Med Rep
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  • The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis. Luo X et al., 2021 Mar 26, Cell Death Dis
    Read more