ProductsBack/PI3 kinase p85 (phospho Tyr467)/p55 (phospho Tyr199) antibody

Untreated (–) and treated (+) C2C12 whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PI3 kinase p85 (phospho Tyr467)/p55 (phospho Tyr199) antibody (GTX132597) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

PI3 kinase p85 (phospho Tyr467)/p55 (phospho Tyr199) antibody

GTX132597

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetPIK3R1

Overview

Supplier
GeneTex
Product Name
PI3 kinase p85 (phospho Tyr467)/p55 (phospho Tyr199) antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1.02 mg/ml
Conjugate
Unconjugated
Gene ID5295
Target name
PIK3R1
Target description
phosphoinositide-3-kinase regulatory subunit 1
Target synonyms
AGM7, GRB1, IMD36, p85, p85-ALPHA, p85alpha, phosphatidylinositol 3-kinase regulatory subunit alpha, PI3 kinase-associated p85, PI3-kinase subunit p85-alpha, PI3K regulatory subunit alpha, growth factor receptor bound 1, phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha), phosphatidylinositol 3-kinase-associated p-85 alpha, phosphoinositide-3-kinase regulatory subunit alpha, phosphoinositide-3-kinase, regulatory subunit 1 (alpha), ptdIns-3-kinase regulatory subunit alpha
Host
Rabbit
Isotype
IgG
Protein IDP27986
Protein Name
Phosphatidylinositol 3-kinase regulatory subunit alpha
Scientific Description
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Nie Q, Cao H, Yang J, et al. PI3K/Akt signalling pathway-associated long noncoding RNA signature predicts the prognosis of laryngeal cancer patients. Sci Rep. 2023,13(1):14764. doi: 10.1038/s41598-023-41927-3
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Pérez-Mora S, Ocampo-López J, Gómez-García MDC, et al. BFNB Enhances Hair Growth in C57BL/6 Mice through the Induction of EGF and FGF7 Factors and the PI3K-AKT-β-Catenin Pathway. Int J Mol Sci. 2023,24(15). doi: 10.3390/ijms241512110
Read this paper
Chen M, Zhang Y, Zeng S, et al. CD36 regulates diurnal glucose metabolism and hepatic clock to maintain glucose homeostasis in mice. iScience. 2023,26(4):106524. doi: 10.1016/j.isci.2023.106524
Read this paper
Li M, Zhang W, Wang Y, et al. DDTC Suppresses Ovarian Cancer Development via the PI3K/AKT/mTOR Signaling Pathway. Dis Markers. 2022,2022:1941077. doi: 10.1155/2022/1941077
Read this paper
Chen J, Sun J, Wang Q, et al. Systemic Deficiency of PTEN Accelerates Breast Cancer Growth and Metastasis. Front Oncol. 2022,12:825484. doi: 10.3389/fonc.2022.825484
Read this paper
Yang L, Lei JF, Ouyang JY, et al. Effect of Neurorepair for Motor Functional Recovery Enhanced by Total Saponins From Trillium tschonoskii Maxim. Treatment in a Rat Model of Focal Ischemia. Front Pharmacol. 2021,12:763181. doi: 10.3389/fphar.2021.763181
Read this paper
Chiou TT, Chau YY, Chen JB, et al. Rapamycin attenuates PLA2R activation-mediated podocyte apoptosis via the PI3K/AKT/mTOR pathway. Biomed Pharmacother. 2021,144:112349. doi: 10.1016/j.biopha.2021.112349
Read this paper
Li M, Zhang W, Yang L, et al. The Mechanism of Xiaoyao San in the Treatment of Ovarian Cancer by Network Pharmacology and the Effect of Stigmasterol on the PI3K/Akt Pathway. Dis Markers. 2021,2021:4304507. doi: 10.1155/2021/4304507
Read this paper
Huang G, Zhang J, Qing G, et al. Downregulation of miR‑483‑5p inhibits TGF‑β1‑induced EMT by targeting RhoGDI1 in pulmonary fibrosis. Mol Med Rep. 2021,24(1):pii: 538. doi: 10.3892/mmr.2021.12177.
Read this paper
Luo X, Zheng E, Wei L, et al. The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis. Cell Death Dis. 2021,12(4):328. doi: 10.1038/s41419-021-03596-w
Read this paper

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PI3 kinase p85 (phospho Tyr467)/p55 (phospho Tyr199) antibody

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