PI3 kinase p85 (phospho Tyr467)/p55 (phospho Tyr199) antibody
GTX132597
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPIK3R1
Overview
- SupplierGeneTex
- Product NamePI3 kinase p85 (phospho Tyr467)/p55 (phospho Tyr199) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.02 mg/ml
- ConjugateUnconjugated
- Gene ID5295
- Target namePIK3R1
- Target descriptionphosphoinositide-3-kinase regulatory subunit 1
- Target synonymsAGM7; GRB1; IMD36; p85; p85-ALPHA; phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; phosphatidylinositol 3-kinase regulatory subunit alpha; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); phosphatidylinositol 3-kinase-associated p-85 alpha; phosphoinositide-3-kinase regulatory subunit alpha; phosphoinositide-3-kinase, regulatory subunit 1 (alpha); PI3K regulatory subunit alpha; PI3-kinase subunit p85-alpha; ptdIns-3-kinase regulatory subunit alpha
- HostRabbit
- IsotypeIgG
- Protein IDP27986
- Protein NamePhosphatidylinositol 3-kinase regulatory subunit alpha
- Scientific DescriptionPhosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- PI3K/Akt signalling pathway-associated long noncoding RNA signature predicts the prognosis of laryngeal cancer patients.Read more
- BFNB Enhances Hair Growth in C57BL/6 Mice through the Induction of EGF and FGF7 Factors and the PI3K-AKT-beta-Catenin Pathway.Read more
- CD36 regulates diurnal glucose metabolism and hepatic clock to maintain glucose homeostasis in mice.Read more
- DDTC Suppresses Ovarian Cancer Development via the PI3K/AKT/mTOR Signaling Pathway.Read more
- Systemic Deficiency of PTEN Accelerates Breast Cancer Growth and Metastasis. Chen J et al., 2022, Front OncolRead more
- Effect of Neurorepair for Motor Functional Recovery Enhanced by Total Saponins From Trillium tschonoskii Maxim. Treatment in a Rat Model of Focal Ischemia. Yang L et al., 2021, Front PharmacolRead more
- Rapamycin attenuates PLA2R activation-mediated podocyte apoptosis via the PI3K/AKT/mTOR pathway. Chiou TT et al., 2021 Dec, Biomed PharmacotherRead more
- The Mechanism of Xiaoyao San in the Treatment of Ovarian Cancer by Network Pharmacology and the Effect of Stigmasterol on the PI3K/Akt Pathway. Li M et al., 2021, Dis MarkersRead more
- Downregulation of miR-483-5p inhibits TGF-beta1-induced EMT by targeting RhoGDI1 in pulmonary fibrosis. Huang G et al., 2021 Jul, Mol Med RepRead more
- The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis. Luo X et al., 2021 Mar 26, Cell Death DisRead more