IHC-P analysis of squamous cell carcinoma of oropharangeal tissue using GTX01927 PLK1 antibody [MJS1]. Note the intense nuclear and cytoplasmic staining of a proportion of proliferating malignant cells.
PLK1 antibody [MJS1]
GTX01927
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetPLK1
Overview
- SupplierGeneTex
- Product NamePLK1 antibody [MJS1]
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMJS1
- ConjugateUnconjugated
- Gene ID5347
- Target namePLK1
- Target descriptionpolo like kinase 1
- Target synonymscell cycle regulated protein kinase; PLK; PLK-1; polo (Drosophia)-like kinase; serine/threonine-protein kinase 13; serine/threonine-protein kinase PLK1; STPK13
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203