Western blot analysis of extracts of various cell lines using PLOD1 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using PLOD1 Polyclonal Antibody at 1:1000 dilution.
PLOD1 Polyclonal Antibody
E-AB-62166
Product group Antibodies
Overview
- SupplierElabscience
- Product NamePLOD1 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionLysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.
- UNSPSC12352203