PLOD1 Polyclonal Antibody

Reddot Biotech

PLOD1 Polyclonal Antibody

5

ImmunoFluorescence

Research Use Only

1 mg/ml

Unconjugated

PLOD1

procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

EDS6; EDSKCL1; LH; LH1; LLH; lysine hydroxylase; lysyl hydroxlase 1; PLOD; procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1; procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

Rabbit

IgG

Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.

Human, Mouse

-20°C

12352203