Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA018229LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA018229LA01HU at dilution of 1:100
PMAIP1 Antibody
CSB-PA018229LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetPMAIP1
Overview
- SupplierCusabio
- Product NamePMAIP1 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID5366
- Target namePMAIP1
- Target descriptionphorbol-12-myristate-13-acetate-induced protein 1
- Target synonymsadult T cell leukemia-derived PMA-responsive; APR; immediate-early-response protein APR; NOXA; phorbol-12-myristate-13-acetate-induced protein 1; PMA-induced protein 1; protein Noxa
- HostRabbit
- IsotypeIgG
- Protein IDQ13794
- Protein NamePhorbol-12-myristate-13-acetate-induced protein 1
- Scientific DescriptionPromotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203