PPAR alpha antibody
GTX101098
ApplicationsImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetPPARA
Overview
- SupplierGeneTex
- Product NamePPAR alpha antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.04 mg/ml
- ConjugateUnconjugated
- Gene ID5465
- Target namePPARA
- Target descriptionperoxisome proliferator activated receptor alpha
- Target synonymshPPAR; NR1C1; nuclear receptor subfamily 1 group C member 1; peroxisome proliferative activated receptor, alpha; peroxisome proliferator-activated nuclear receptor alpha variant 3; peroxisome proliferator-activated receptor alpha; PPAR; PPARalpha; PPAR-alpha
- HostRabbit
- IsotypeIgG
- Protein IDQ07869
- Protein NamePeroxisome proliferator-activated receptor alpha
- Scientific DescriptionPeroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions.Read more
- Berberine Reduces Lipid Accumulation in Obesity via Mediating Transcriptional Function of PPARdelta.Read more
- Selective activation of PPARalpha maintains thermogenic capacity of beige adipocytes.Read more
- Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity.Read more
- Extremely low-frequency pulses of faint magnetic field induce mitophagy to rejuvenate mitochondria. Toda T et al., 2022 May 12, Commun BiolRead more
- Consumption of Non-Nutritive Sweetener, Acesulfame Potassium Exacerbates Atherosclerosis through Dysregulation of Lipid Metabolism in ApoE-/- Mice. Lin CH et al., 2021 Nov 9, NutrientsRead more
- Alleviative Effect of Ruellia tuberosa L. on Insulin Resistance and Abnormal Lipid Accumulation in TNF-alpha-Treated FL83B Mouse Hepatocytes. Chen HJ et al., 2021, Evid Based Complement Alternat MedRead more
- Glavonoid-rich oil supplementation reduces stearoyl-coenzyme A desaturase 1 expression and improves systemic metabolism in diabetic, obese KK-Ay mice. Igarashi Y et al., 2021 Aug, Biomed PharmacotherRead more
- Curcumin promotes AApoAII amyloidosis and peroxisome proliferation in mice by activating the PPARalpha signaling pathway. Dai J et al., 2021 Jan 26, ElifeRead more
- Upregulation of peroxisome proliferator-activated receptor-alpha and the lipid metabolism pathway promotes carcinogenesis of ampullary cancer. Wang CY et al., 2021, Int J Med SciRead more
![WB analysis of 25 ug of Hela (Lane 1), Jurkat (Lane 2), and NIH-3T3 cell lysates (Lane 3) using GTX12412 PPAR alpha antibody [3B6/PPAR]. Dilution : 1:1000 (lane 1 and 2) & 1:500 (lane 3)](https://www.genetex.com/upload/website/prouct_img/normal/GTX12412/GTX12412_1480_WB_w_23060522_816.webp)





![FACS analysis of 3T3 cells using GTX12412 PPAR alpha antibody [3B6/PPAR] compared to an isotype control (blue). Dilution : 0.25 ug/test for 60 min at room temperature Fixation : 2% paraformaldehyde](https://www.genetex.com/upload/website/prouct_img/normal/GTX22779/GTX22779_138_FACS_w_23060620_338.webp)