IHC-P analysis of human melanoma tissue section using GTX03315 PRAME antibody [EPR20330].
IHC-P analysis of human melanoma tissue section using GTX03315 PRAME antibody [EPR20330].
PRAME antibody [EPR20330]
GTX03315
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetPRAME
Overview
- SupplierGeneTex
- Product NamePRAME antibody [EPR20330]
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDEPR20330
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID23532
- Target namePRAME
- Target descriptionPRAME nuclear receptor transcriptional regulator
- Target synonymscancer/testis antigen 130; CT130; MAPE; melanoma antigen preferentially expressed in tumors; OIP4; OIP-4; opa-interacting protein 4; Opa-interacting protein OIP4; preferentially expressed antigen in melanoma; preferentially expressed antigen of melanoma
- HostRabbit
- IsotypeIgG
- Protein IDP78395
- Protein NameMelanoma antigen preferentially expressed in tumors
- Scientific DescriptionThis gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203