PRAME antibody [EPR20330]

GeneTex

PRAME antibody [EPR20330]

9

IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

EPR20330

Unconjugated

PRAME

PRAME nuclear receptor transcriptional regulator

CT130, MAPE, OIP-4, OIP4, melanoma antigen preferentially expressed in tumors, Opa-interacting protein OIP4, cancer/testis antigen 130, opa-interacting protein 4, preferentially expressed antigen in melanoma, preferentially expressed antigen of melanoma

Rabbit

IgG

Melanoma antigen preferentially expressed in tumors

This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Human

2°C to 8°C

12352203