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ProductsBack/PRAME antibody

WB analysis of HepG2 cell lysates using GTX03709 PRAME antibody. The lane on the left was treated with blocking peptide.

WB analysis of HepG2 cell lysates using GTX03709 PRAME antibody. The lane on the left was treated with blocking peptide.

WB analysis of HepG2 cell lysates using GTX03709 PRAME antibody. The lane on the left was treated with blocking peptide.

PRAME antibody

GTX03709

ApplicationsWestern Blot

Product group Antibodies

ReactivityHuman, Mouse

TargetPRAME

Overview

Supplier
GeneTex
Product Name
PRAME antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID23532
Target name
PRAME
Target description
PRAME nuclear receptor transcriptional regulator
Target synonyms
CT130, MAPE, OIP-4, OIP4, melanoma antigen preferentially expressed in tumors, Opa-interacting protein OIP4, cancer/testis antigen 130, opa-interacting protein 4, preferentially expressed antigen in melanoma, preferentially expressed antigen of melanoma
Host
Rabbit
Isotype
IgG
Protein IDP78395
Protein Name
Melanoma antigen preferentially expressed in tumors
Scientific Description
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

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