
Immunohistochemical analysis of paraffin-embedded human breast cancer using Progesterone Receptor antibody (GTX116051) diluted at 1:500. Representative data showing negative staining in PR-negative breast cancer (left) and nuclear staining in PR-positive breast cancer (right).
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
Progesterone Receptor antibody [N1], N-term
GTX116051
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetPGR
Overview
- SupplierGeneTex
- Product NameProgesterone Receptor antibody [N1], N-term
- Delivery Days Customer9
- Application Supplier NoteICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.33 mg/ml
- ConjugateUnconjugated
- Gene ID5241
- Target namePGR
- Target descriptionprogesterone receptor
- Target synonymsNR3C3, PR, progesterone receptor, nuclear receptor subfamily 3 group C member 3
- HostRabbit
- IsotypeIgG
- Protein IDP06401
- Protein NameProgesterone receptor
- Scientific DescriptionThis gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC41116161






