Purified Anti-Human CD11a Antibody

Reddot Biotech

Purified Anti-Human CD11a Antibody

5

Flow Cytometry

Research Use Only

Monoclonal

R7-1

0.5 mg/ml

Unconjugated

ITGAL

integrin subunit alpha L

CD11A, LFA-1, LFA1A, integrin alpha-L, CD11 antigen-like family member A, LFA-1 alpha, LFA-1A, antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide, integrin gene promoter, integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), leukocyte adhesion glycoprotein LFA-1 alpha chain, leukocyte function-associated molecule 1 alpha chain, lymphocyte function-associated antigen 1, alpha polypeptide

Mouse

IgG1

CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1Oe+/- chain and integrin Oe+/-L subunit. CD11a non-covalently associates with integrin beta2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

Human

2°C to 8°C

12352203