PVRL4 antibody [HL2758]
GTX639621
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetNECTIN4
Overview
- SupplierGeneTex
- Product NamePVRL4 antibody [HL2758]
- Delivery Days Customer9
- Antibody SpecificityThis antibody was raised against human PVRL4 Extracellular domain.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHL2758
- ConjugateUnconjugated
- Gene ID81607
- Target nameNECTIN4
- Target descriptionnectin cell adhesion molecule 4
- Target synonymsEDSS1; Ig superfamily receptor LNIR; LNIR; nectin 4; nectin-4; poliovirus receptor-related 4; poliovirus receptor-related protein 4; PRR4; PVRL4
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203