Bio-Connect

PVRL4 antibody [HL2758]

Research Use Only
GTX639621
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetNECTIN4
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    PVRL4 antibody [HL2758]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody was raised against human PVRL4 Extracellular domain.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HL2758
  • Conjugate
    Unconjugated
  • Gene ID81607
  • Target name
    NECTIN4
  • Target description
    nectin cell adhesion molecule 4
  • Target synonyms
    EDSS1; Ig superfamily receptor LNIR; LNIR; nectin 4; nectin-4; poliovirus receptor-related 4; poliovirus receptor-related protein 4; PRR4; PVRL4
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C or -80°C
  • UNSPSC
    12352203