PVRL4 antibody [HL3520]

GeneTex

PVRL4 antibody [HL3520]

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

HL3520

1 mg/ml

Unconjugated

NECTIN4

nectin cell adhesion molecule 4

EDSS1; Ig superfamily receptor LNIR; LNIR; nectin 4; nectin-4; poliovirus receptor-related 4; poliovirus receptor-related protein 4; PRR4; PVRL4

Rabbit

IgG

Nectin-4

This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]

-20°C or -80°C,2°C to 8°C

12352203