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ProductsBack/Quercetin . dihydrate [6151-25-3]
Chemical Structure
Chemical Structure
Chemical Structure

Quercetin . dihydrate [6151-25-3]

Research Use Only
AG-CN2-0409
AdipoGen Life Sciences
CAS Number6151-25-3
DownloadMSDS
Product group Chemicals
Estimated Purity>95%
Molecular Weight302.2 . 36.0
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Quercetin . dihydrate
  • Delivery Days Customer
    10
  • ADR Class
    6.1
  • CAS Number
    6151-25-3
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Danger,Excepted quantity
  • Molecular Formula
    C15H10O7 . 2H20
  • Molecular Weight
    302.2 . 36.0
  • Scientific Description
    Chemical. CAS: 6151-25-3. Formula: C15H10O7 . 2H20. MW: 302.2 . 36.0. Isolated from Umbelliferae sp. Multipotent flavonoid antioxidant. Potent free radical scavenger. Neuroprotective. Anticancer compound with chemosensitizing activity. Cell cycle arrest, apoptosis and autophagy inducer. Proteasome inhibitor. Pleiotropic kinase inhibitor, including tyrosine protein kinase (Trk), mitochondrial ATPase, cAMP- and cGMP-phosphodiesterases, PI3-kinase activity, phospholipase A2 and protein kinase C (PKC). DNA topoisomerases inhibitor. SIRT1 activator. Heat shock proteins inhibitor. Reversible fatty acid synthase inhibitor. Antithrombotic, antihistaminic and anti-inflammatory agent. Monoamine oxidase inhibitor. Vasodilatory compound. anti-diabetic compound. - Multipotent flavonoid antioxidant. Potent free radical scavenger. Neuroprotective. Anticancer compound with chemosensitizing activity. Cell cycle arrest, apoptosis and autophagy inducer. Proteasome inhibitor. Pleiotropic kinase inhibitor, including tyrosine protein kinase (Trk), mitochondrial ATPase, cAMP- and cGMP-phosphodiesterases, PI3-kinase activity, phospholipase A2 and protein kinase C (PKC). DNA topoisomerases inhibitor. SIRT1 activator. Heat shock proteins inhibitor. Reversible fatty acid synthase inhibitor. Antithrombotic, antihistaminic and anti-inflammatory agent. Monoamine oxidase inhibitor. Vasodilatory compound. Anti-diabetic compound. Antiviral for the prevention and treatment of SARS-CoV-2 related disease (COVID-19)
  • SMILES
    OC1=CC(O)=C2C(OC(=C(O)C2=O)C2=CC=C(O)C(O)=C2)=C1
  • Storage Instruction
    2°C to 8°C
  • UN Number
    UN 2811
  • UNSPSC
    12352200

References

  • Pharmacological inhibitors of Fatty Acid Synthase (FASN) - catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents? R. Lupu & J.A. Menendez; Curr. Pharm. Biotechnol. 7, 483 (2006) (Review)
  • Health effects of quercetin: from antioxidant to nutraceutical: A.W. Boots, et al.; Eur. J. Pharmacol. 585, 325 (2008) (Review)
  • Multitargeted cancer prevention by quercetin: A. Murakami, et al.; Cancer Lett. 269, 315 (2008) (Review)
  • Inhibiting the transcription factor HSF1 as an anticancer strategy: L. Whitesell & S. Lindquist; Expert Opin. Ther. Targets 13, 469 (2009) (Review)
  • In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity: K.H. Tiong, et al.; Xenobiotica 40, 458 (2010) (Review)
  • Regulation of SIRT1 in cellular functions: role of polyphenols: S. Chung, et al.; Arch. Biochem. Biophys. 501, 79 (2010) (Review)
  • Quercetin as a systemic chemopreventative agent: structural and functional mechanisms: E.E. Mendoza & R. Burd; Mini Rev. Med. Chem. 11, 1216 (2011) (Review)
  • Exploiting tyrosinase expression and activity in melanocytic tumors: quercetin and the central role of p53: A.J. Vargas, et al.; Integr. Cancer Ther. 10, 328 (2011) (Review)
  • Targeting tumor ubiquitin-proteasome pathway with polyphenols for chemosensitization: M. Shen, et al.; Anticancer Agents Med. Chem. 12, 891 (2012) (Review)
  • Flavonoids acting on DNA topoisomerases: recent advances and future perspectives in cancer therapy: P. Russo, et al.; Curr. Med. Chem. 19, 5287 (2012) (Review)