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Western blot analysis of extracts of various cell lines using RAD51 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using RAD51 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using RAD51 Polyclonal Antibody at dilution of 1:1000.

RAD51 Polyclonal Antibody

E-AB-62189
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    RAD51 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.
  • UNSPSC
    12352203