Rb antibody

GeneTex

Rb antibody [Rb]

9

IHC-Fr: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 105 kDa. Optimal dilutions/concentrations should be determined by the end user.

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

1.1 mg/ml

Unconjugated

RB1

RB transcriptional corepressor 1

OSRC, PPP1R130, RB, p105-Rb, p110-RB1, pRb, pp110, retinoblastoma-associated protein, prepro-retinoblastoma-associated protein, protein phosphatase 1, regulatory subunit 130, retinoblastoma 1, retinoblastoma suspectibility protein

Mouse

IgG1

Retinoblastoma-associated protein

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203