The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA070474(RBFOX3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)

RBFOX3 Antibody

Name: RBFOX3 Antibody
SKU: CSB-PA070474_C90
Availability: BackOrder

CSB-PA070474

ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

TargetRBFOX3

Overview

Supplier
Cusabio
Product Name
RBFOX3 Antibody
Delivery Days Customer
20
Applications
Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID146713
Target name
RBFOX3
Target description
RNA binding fox-1 homolog 3
Target synonyms
fox-1 homolog C; FOX3; FOX-3; hexaribonucleotide binding protein 3; HRNBP3; NEUN; neuN antigen; neuronal nuclei antigen; RNA binding protein fox-1 homolog 3; RNA binding protein, fox-1 homolog 3
Host
Rabbit
Isotype
IgG
Protein IDA6NFN3
Protein Name
RNA binding protein fox-1 homolog 3
Scientific Description
Immunoprecipitation and mass spectrometry of the two major NeuN species at 45-50 kDa identified both as the RNA binding protein Rbfox3 (a member of the Fox family of alternative splicing factors), confirming and extending the identification of the 45 kDa band as Rbfox3. Mapping of the anti-NeuN reactive epitopes in both R3hdm2 and Rbfox3 reveals a common proline- and glutamine-rich domain that lies at the N-terminus of the Rbfox3 protein. Nuclear Rbfox3 isoforms can also enhance the inclusion of cryptic exons in the Rbfox2 mRNA, resulting in nonsense-mediated decay of the message, thereby contributing to the negative regulation of Rbfox2 by Rbfox3 through a novel mechanism.
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

RBFOX3 Antibody

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Overview

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