![Renin Receptor antibody [N3C3] detects Renin Receptor protein by immunofluorescent analysis. Sample: DIV9 rat hippocampal neuron cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Renin Receptor stained by Renin Receptor antibody [N3C3] (GTX114169) diluted at 1:500. Red: Tau, an axon marker, stained by Tau antibody [GT287] (GTX634809) diluted at 1:500. Blue: Fluoroshield with DAPI (GTX30920). Renin Receptor antibody [N3C3] detects Renin Receptor protein by immunofluorescent analysis. Sample: DIV9 rat hippocampal neuron cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Renin Receptor stained by Renin Receptor antibody [N3C3] (GTX114169) diluted at 1:500. Red: Tau, an axon marker, stained by Tau antibody [GT287] (GTX634809) diluted at 1:500. Blue: Fluoroshield with DAPI (GTX30920).](https://www.genetex.com/upload/website/prouct_img/normal/GTX114169/GTX114169_43810_20211008_ICC_IF_R_w_23060501_403.webp)
Renin Receptor antibody [N3C3] detects Renin Receptor protein by immunofluorescent analysis. Sample: DIV9 rat hippocampal neuron cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Renin Receptor stained by Renin Receptor antibody [N3C3] (GTX114169) diluted at 1:500. Red: Tau, an axon marker, stained by Tau antibody [GT287] (GTX634809) diluted at 1:500. Blue: Fluoroshield with DAPI (GTX30920).
Renin Receptor antibody [N3C3]
GTX114169
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetATP6AP2
Overview
- SupplierGeneTex
- Product NameRenin Receptor antibody [N3C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.38 mg/ml
- ConjugateUnconjugated
- Gene ID10159
- Target nameATP6AP2
- Target descriptionATPase H+ transporting accessory protein 2
- Target synonyms(P)RR, APT6M8-9, ATP6IP2, ATP6M8-9, CDG2R, ELDF10, HT028, M8-9, MRXE, MRXSH, MSTP009, PRR, RENR, XMRE, XPDS, renin receptor, ATPase H(+)-transporting lysosomal-interacting protein 2, ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8-9, ATPase, H+ transporting, lysosomal accessory protein 2, ATPase, H+ transporting, lysosomal interacting protein 2, ER-localized type I transmembrane adapter, ER-localized type I transmembrane adaptor, N14F, V-ATPase M8.9 subunit, embryonic liver differentiation factor 10, prorenin receptor, renin/prorenin receptor, vacuolar ATP synthase membrane sector-associated protein M8-9, vacuolar proton ATP synthase membrane sector associated protein M8-9
- HostRabbit
- IsotypeIgG
- Protein IDO75787
- Protein NameRenin receptor
- Scientific DescriptionThis gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Mohammad AH, Couture F, Gamache I, et al. Cleavage of the V-ATPase associated prorenin receptor is mediated by PACE4 and is essential for growth of prostate cancer cells. PLoS One. 2023,18(7):e0288622. doi: 10.1371/journal.pone.0288622Read this paper
- Mohammad AH, Kim SH, Bertos N, et al. Elevated V-ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer. Mol Cancer Res. 2020,18(10):1477-1490. doi: 10.1158/1541-7786.MCR-20-0088Read this paper
- Mohammad AH, Assadian S, Couture F, et al. V-ATPase-associated prorenin receptor is upregulated in prostate cancer after PTEN loss. Oncotarget. 2019,10(48):4923-4936. doi: 10.18632/oncotarget.27075Read this paper
- Ding L, Zhang G, Hou Y, et al. Elemene inhibits osteosarcoma growth by suppressing the renin‑angiotensin system signaling pathway. Mol Med Rep. 2018,17(1):1022-1030. doi: 10.3892/mmr.2017.7965Read this paper
- Arundhathi A, Chuang WH, Chen JK, et al. Prorenin receptor acts as a potential molecular target for pancreatic ductal adenocarcinoma diagnosis. Oncotarget. 2016,7(34):55437-55448. doi: 10.18632/oncotarget.10583Read this paper
- Nakagawa T, Suzuki-Nakagawa C, Watanabe A, et al. Site-1 protease is required for the generation of soluble (pro)renin receptor. J Biochem. 2017,161(4):369-379. doi: 10.1093/jb/mvw080Read this paper
- Suzuki-Nakagawa C, Nishimura M, Tsukamoto T, et al. Participation of the extracellular domain in (pro)renin receptor dimerization. Biochem Biophys Res Commun. 2014,444(4):461-6. doi: 10.1016/j.bbrc.2014.01.073Read this paper

![Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Renin Receptor antibody [N3C3] (GTX114169) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Renin Receptor antibody [N3C3] (GTX114169) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.](https://www.genetex.com/upload/website/prouct_img/normal/GTX114169/GTX114169_43810_20191227_WB_w_23060501_893.webp)











