WB analysis of various sample lysates using GTX46918 RNF43 antibody, Internal. Dilution : 1microg/ml Loading : 25microg
WB analysis of various sample lysates using GTX46918 RNF43 antibody, Internal. Dilution : 1microg/ml Loading : 25microg
RNF43 antibody, Internal
GTX46918
Overview
- SupplierGeneTex
- Product NameRNF43 antibody, Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID54894
- Target nameRNF43
- Target descriptionring finger protein 43
- Target synonymsE3 ubiquitin-protein ligase RNF43; RING-type E3 ubiquitin transferase RNF43; RNF124; SSPCS; URCC
- HostRabbit
- IsotypeIgG
- Protein IDQ68DV7
- Protein NameE3 ubiquitin-protein ligase RNF43
- Scientific DescriptionThe protein encoded by this gene is a RING-type E3 ubiquitin ligase and is predicted to contain a transmembrane domain, a protease-associated domain, an ectodomain, and a cytoplasmic RING domain. This protein is thought to negatively regulate Wnt signaling, and expression of this gene results in an increase in ubiquitination of frizzled receptors, an alteration in their subcellular distribution, resulting in reduced surface levels of these receptors. Mutations in this gene have been reported in multiple tumor cells, including colorectal and endometrial cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203