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RPLP0 antibody

Research Use Only
GTX114730
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetRPLP0
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Overview

  • Supplier
    GeneTex
  • Product Name
    RPLP0 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.34 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID6175
  • Target name
    RPLP0
  • Target description
    ribosomal protein lateral stalk subunit P0
  • Target synonyms
    60S acidic ribosomal protein P0; 60S ribosomal protein L10E; acidic ribosomal phosphoprotein P0; L10E; large ribosomal subunit protein uL10; LP0; neutral ribosomal phosphoprotein P0; P0; PRLP0; ribosomal protein, large, P0; RPP0
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP05388
  • Protein Name
    60S acidic ribosomal protein P0
  • Scientific Description
    Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Pathological Tau Promotes Neuronal Damage by Impairing Ribosomal Function and Decreasing Protein Synthesis. Meier S et al., 2016 Jan 20, J Neurosci
    Read more
  • Identification of Novel Tau Interactions with Endoplasmic Reticulum Proteins in Alzheimers Disease Brain. Meier S et al., 2015, J Alzheimers Dis
    Read more