RUNX1 antibody [2B5]

GeneTex

RUNX1 antibody [2B5]

9

WB: 1/500 - 1/2000. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA

Research Use Only

Monoclonal

2B5

Unconjugated

RUNX1

RUNX family transcription factor 1

acute myeloid leukemia 1 protein; AML1; AML1-ETO fusion; AML1-ETO fusion protein; AML1-EVI-1; AML1-EVI-1 fusion protein; AMLCR1; CBF2alpha; CBFA2; core-binding factor, runt domain, alpha subunit 2; EVI-1; mutant RUNX1; oncogene AML-1; PEA2-alpha B; PEBP2aB; PEBP2alpha; PEBP2-alpha B; polyomavirus enhancer-binding protein 2 alpha B subunit; runt related transcription factor 1; runt-related transcription factor 1; SL3/AKV core-binding factor alpha B subunit; SL3-3 enhancer factor 1 alpha B subunit

Mouse

IgG1

Runt-related transcription factor 1

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203