Ruxolitinib (INCB018424) [941678-49-5]
S1378
CAS Number941678-49-5
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameRuxolitinib (INCB018424) [941678-49-5]
- Delivery Days Customer9
- CAS Number941678-49-5
- CertificationResearch Use Only
- Scientific DescriptionRuxolitinib (INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis.
- UNSPSC12352200
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