S-arrestin antibody [PDS-1]

GeneTex

S-arrestin antibody [PDS-1]

9

S-arrestin in retina from porcine, human, bovine & weakly with rat, and shows heteroclitic behaviour

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

PDS-1

Unconjugated

SAG

S-antigen visual arrestin

48 kDa protein; arrestin 1; retinal S-antigen (48 KDa protein); rod arrestin; rod photoreceptor arrestin; RP47; S-AG; S-antigen; retina and pineal gland (arrestin); S-arrestin

Mouse

IgG1

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq, Jul 2008]

Bovine, Human, Porcine, Rat

2°C to 8°C,-20°C or -80°C

12352203