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ProductsBack/SIN3A Recombinant Monoclonal Antibody
Western Blot Positive WB detected in: K562 whole cell lysate, MCF-7 whole cell lysate All lanes: mSin3A antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 146 kDa Observed band size: 146 kDa
Western Blot Positive WB detected in: K562 whole cell lysate, MCF-7 whole cell lysate All lanes: mSin3A antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 146 kDa Observed band size: 146 kDa
Western Blot Positive WB detected in: K562 whole cell lysate, MCF-7 whole cell lysate All lanes: mSin3A antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 146 kDa Observed band size: 146 kDa

SIN3A Recombinant Monoclonal Antibody

CSB-RA242724A0HU
Cusabio
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSIN3A
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Overview

  • Supplier
    Cusabio
  • Product Name
    SIN3A Recombinant Monoclonal Antibody
  • Delivery Days Customer
    20
  • Applications
    ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    10G3
  • Conjugate
    Unconjugated
  • Gene ID25942
  • Target name
    SIN3A
  • Target description
    SIN3 transcription regulator family member A
  • Target synonyms
    histone deacetylase complex subunit Sin3a; paired amphipathic helix protein Sin3a; SIN3 homolog A, transcription regulator; transcriptional corepressor Sin3a; transcriptional co-repressor Sin3A; transcriptional regulator, SIN3A; WITKOS
  • Isotype
    IgG
  • Protein IDQ96ST3
  • Protein Name
    Paired amphipathic helix protein Sin3a
  • Scientific Description
    Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression (By similarity).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203