SOCS3 antibody [N1C3]
GTX113049
Overview
- SupplierGeneTex
- Product NameSOCS3 antibody [N1C3]
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.7 mg/ml
- ConjugateUnconjugated
- Gene ID9021
- Target nameSOCS3
- Target descriptionsuppressor of cytokine signaling 3
- Target synonymsATOD4; CIS3; Cish3; cytokine-inducible SH2 protein 3; SOCS-3; SSI3; SSI-3; STAT-induced STAT inhibitor 3; suppressor of cytokine signaling 3
- HostRabbit
- IsotypeIgG
- Protein IDO14543
- Protein NameSuppressor of cytokine signaling 3
- Scientific DescriptionThis gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Testosterone regulates the intracellular bacterial community formation of uropathogenic Escherichia coli in prostate cells via STAT3. Ho CH et al., 2020 Oct, Int J Med MicrobiolRead more