SOX2 antibody [GT1352]
GTX627405
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetSOX2
Overview
- SupplierGeneTex
- Product NameSOX2 antibody [GT1352]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. FACS: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT1352
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID6657
- Target nameSOX2
- Target descriptionSRY-box transcription factor 2
- Target synonymsANOP3; MCOPS3; sex determining region Y-box 2; SRY (sex determining region Y)-box 2; SRY-box 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2
- HostMouse
- IsotypeIgG2a
- Protein IDP48431
- Protein NameTranscription factor SOX-2
- Scientific DescriptionThis intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewings sarcoma cells. Kitagawa T et al., 2022, PLoS OneRead more
- The aqueous extract of brucea javanica reduces tumorigenicity of human lung cancer tumorspheres. Kim SH et al., 2021, Cancer Drug ResistRead more
- Chlorpromazine affects the numbers of Sox-2, Musashi1 and DCX-expressing cells in the rat brain subventricular zone. Skalbania J et al., 2021 Aug, Pharmacol RepRead more
- From ACTH-Dependent to ACTH-Independent Cushings Syndrome from a Malignant Mixed Corticomedullary Adrenal Tumor: Potential Role of Embryonic Stem Cells. Ramirez-Renteria C et al., 2020, Case Rep EndocrinolRead more
- Comprehensive Exploration to Identify Predictive DNA Markers of deltaNp63/SOX2 in Drug Resistance in Human Esophageal Squamous Cell Carcinoma. Ooizumi Y et al., 2019 Dec, Ann Surg OncolRead more
- Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2. Yang SC et al., 2019 Sep, FASEB JRead more