Bio-Connect

SOX2 antibody [GT1352]

GTX627405
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetSOX2
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    SOX2 antibody [GT1352]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. FACS: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GT1352
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6657
  • Target name
    SOX2
  • Target description
    SRY-box transcription factor 2
  • Target synonyms
    ANOP3; MCOPS3; sex determining region Y-box 2; SRY (sex determining region Y)-box 2; SRY-box 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP48431
  • Protein Name
    Transcription factor SOX-2
  • Scientific Description
    This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • AT-hook DNA-binding motif-containing protein one knockdown downregulates EWS-FLI1 transcriptional activity in Ewings sarcoma cells. Kitagawa T et al., 2022, PLoS One
    Read more
  • The aqueous extract of brucea javanica reduces tumorigenicity of human lung cancer tumorspheres. Kim SH et al., 2021, Cancer Drug Resist
    Read more
  • Chlorpromazine affects the numbers of Sox-2, Musashi1 and DCX-expressing cells in the rat brain subventricular zone. Skalbania J et al., 2021 Aug, Pharmacol Rep
    Read more
  • From ACTH-Dependent to ACTH-Independent Cushings Syndrome from a Malignant Mixed Corticomedullary Adrenal Tumor: Potential Role of Embryonic Stem Cells. Ramirez-Renteria C et al., 2020, Case Rep Endocrinol
    Read more
  • Comprehensive Exploration to Identify Predictive DNA Markers of deltaNp63/SOX2 in Drug Resistance in Human Esophageal Squamous Cell Carcinoma. Ooizumi Y et al., 2019 Dec, Ann Surg Oncol
    Read more
  • Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2. Yang SC et al., 2019 Sep, FASEB J
    Read more