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SP1 antibody [HL1396] detects SP1 protein at nucleus by immunohistochemical analysis. Sample: Paraffin-embedded mouse intestine. SP1 stained by SP1 antibody [HL1396] (GTX636836) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
SP1 antibody [HL1396] detects SP1 protein at nucleus by immunohistochemical analysis. Sample: Paraffin-embedded mouse intestine. SP1 stained by SP1 antibody [HL1396] (GTX636836) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
SP1 antibody [HL1396] detects SP1 protein at nucleus by immunohistochemical analysis. Sample: Paraffin-embedded mouse intestine. SP1 stained by SP1 antibody [HL1396] (GTX636836) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

SP1 antibody [HL1396]

GTX636836
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSP1
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Overview

  • Supplier
    GeneTex
  • Product Name
    SP1 antibody [HL1396]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HL1396
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6667
  • Target name
    SP1
  • Target description
    Sp1 transcription factor
  • Target synonyms
    transcription factor Sp1, specificity protein 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP08047
  • Protein Name
    Transcription factor Sp1
  • Scientific Description
    The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Fosso E, Leo M, Muccillo L, et al. Quercetin's Dual Mode of Action to Counteract the Sp1-miR-27a Axis in Colorectal Cancer Cells. Antioxidants (Basel). 2023,12(8). doi: 10.3390/antiox12081547
    Read this paper