ICC/IF analysis of MeOH-fixed HeLa cells using GTX17813 SPTBN2 antibody [SPTBN2/1778]. Green : Primary antibody Red : nucleus
SPTBN2 antibody [SPTBN2/1778]
GTX17813
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityHuman
TargetSPTBN2
Overview
- SupplierGeneTex
- Product NameSPTBN2 antibody [SPTBN2/1778]
- Delivery Days Customer9
- Application Supplier NoteWB: 1-2microg/ml. ICC/IF: 1-2microg/ml. IHC-P: 1-2microg/ml for 30 minutes at RT. ELISA: 2-4microg/ml (for coating). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSPTBN2/1778
- Concentration0.2 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID6712
- Target nameSPTBN2
- Target descriptionspectrin beta, non-erythrocytic 2
- Target synonymsbeta-III spectrin; glutamate transporter EAAT4-associated protein 41; GTRAP41; SCA5; SCAR14; spectrin beta chain, brain 2; spectrin beta chain, non-erythrocytic 2; spectrin beta III sigma 2; spectrin, non-erythroid beta chain 2; spinocerebellar ataxia 5 protein
- HostMouse
- IsotypeIgG1
- Protein IDO15020
- Protein NameSpectrin beta chain, non-erythrocytic 2
- Scientific DescriptionSpectrins are principle components of a cells membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203