SPTBN2 antibody [SPTBN2/2894R]

GeneTex

SPTBN2 antibody [SPTBN2/2894R]

9

WB: 1-2 microg/ml. IHC-P: 1-2 microg/ml. FACS: 1-2 microg/million cells. ELISA: 2-4 microg/ml (for coating). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

SPTBN2/2894R

200 ug/ml

Unconjugated

SPTBN2

spectrin beta, non-erythrocytic 2

GTRAP41, SCA5, SCAR14, spectrin beta chain, non-erythrocytic 2, beta-III spectrin, glutamate transporter EAAT4-associated protein 41, spectrin beta III sigma 2, spectrin beta chain, brain 2, spectrin, non-erythroid beta chain 2, spinocerebellar ataxia 5 protein

Rabbit

IgG

Spectrin beta chain, non-erythrocytic 2

Spectrins are principle components of a cells membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]

2°C to 8°C

12352203