
ICC/IF analysis of MDCK cells were left untreated (A), stimulated with H2O2 (1 mM for 10 minutes) (B), or pretreated with PP2 prior to H2O2 stimulation (C) using GTX54529 Src (phospho Tyr416) antibody (Alexa Fluor 488).
Src (phospho Tyr416) antibody (Alexa Fluor 488)
GTX54529
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityCanine, Chicken, Human, Mouse
TargetSRC
Overview
- SupplierGeneTex
- Product NameSrc (phospho Tyr416) antibody (Alexa Fluor 488) - Orthogonal Validated
- Delivery Days Customer9
- Antibody SpecificityBased on sequence homology, this antibody may cross with other Src family members such as YES1 , FYN proteins when phosphorylated at the equivalent sites.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateAlexaFluor 488
- Gene ID6714
- Target nameSRC
- Target descriptionSRC proto-oncogene, non-receptor tyrosine kinase
- Target synonymsASV; c-SRC; p60-Src; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; proto-oncogene tyrosine-protein kinase Src; SRC1; THC6; tyrosine kinase pp60c-src; tyrosine-protein kinase SRC-1; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
- HostRabbit
- IsotypeIgG
- Protein IDP12931
- Protein NameProto-oncogene tyrosine-protein kinase Src
- Scientific DescriptionThis gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
- ReactivityCanine, Chicken, Human, Mouse
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203