ICC/IF analysis of HeLa cells transfected with (A) Tau and (B) Tau + Fyn uaing Tau (phospho Tyr18) antibody at a dilution of 1:200.
![WB analysis of lysates from HeLa cells (4) untransfected and transfected with (1) Tau, (2) Tau + Fyn, (3) Tau + Src, (5) TauY18F, (6) TauY18F + Fyn and (7) TauY18F + Src using Tau (phospho Tyr18) antibody [9G3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX54658/GTX54658_WB_w_23060900_253.webp "WB analysis of lysates from HeLa cells (4) untransfected and transfected with (1) Tau, (2) Tau + Fyn, (3) Tau + Src, (5) TauY18F, (6) TauY18F + Fyn and (7) TauY18F + Src using Tau (phospho Tyr18) antibody [9G3].")
ICC/IF analysis of HeLa cells transfected with (A) Tau and (B) Tau + Fyn uaing Tau (phospho Tyr18) antibody at a dilution of 1:200.
Tau (phospho Tyr18) antibody [9G3]
GTX54658
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMAPT
Overview
- SupplierGeneTex
- Product NameTau (phospho Tyr18) antibody [9G3]
- Delivery Days Customer9
- Application Supplier NoteIF: 1:2000 - 1:5000. IHC: 1:1000 - 1:5000. WB: 1:1000 - 1:5000
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID9G3
- ConjugateUnconjugated
- Gene ID4137
- Target nameMAPT
- Target descriptionmicrotubule associated protein tau
- Target synonymsDDPAC; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; MAPTL; microtubule-associated protein tau; MSTD; MTBT1; MTBT2; neurofibrillary tangle protein; paired helical filament-tau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; TAU; tau-40
- HostMouse
- IsotypeIgG2a
- Protein IDP10636
- Protein NameMicrotubule-associated protein tau
- Scientific DescriptionThis gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimers disease, Picks disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Fyn nanoclustering requires switching to an open conformation and is enhanced by FTLD-Tau biomolecular condensates.Read more
- Vascular smooth muscle cell dysfunction contribute to neuroinflammation and Tau hyperphosphorylation in Alzheimer disease. Aguilar-Pineda JA et al., 2021 Sep 24, iScienceRead more
- Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder. Egervari G et al., 2020 Sep 14, Nat CommunRead more