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Wild-type (WT) and TARDBP knockout (KO) HAP1 cell extracts (50 Aμg) were separated by gradient gel% SDS-PAGE, and the membrane was blotted with TDP43 antibody [GT225] (GTX630196) diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. Data provided byA?YCharOSA?Inc., an open science company with the mission of characterizing commercially available antibody reagents for all human proteins using knockout technology.
Wild-type (WT) and TARDBP knockout (KO) HAP1 cell extracts (50 Aμg) were separated by gradient gel% SDS-PAGE, and the membrane was blotted with TDP43 antibody [GT225] (GTX630196) diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. Data provided byA?YCharOSA?Inc., an open science company with the mission of characterizing commercially available antibody reagents for all human proteins using knockout technology.
Wild-type (WT) and TARDBP knockout (KO) HAP1 cell extracts (50 Aμg) were separated by gradient gel% SDS-PAGE, and the membrane was blotted with TDP43 antibody [GT225] (GTX630196) diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. Data provided byA?YCharOSA?Inc., an open science company with the mission of characterizing commercially available antibody reagents for all human proteins using knockout technology.

TDP43 antibody [GT225]

GTX630196
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTARDBP
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Overview

  • Supplier
    GeneTex
  • Product Name
    TDP43 antibody [GT225]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    GT225
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID23435
  • Target name
    TARDBP
  • Target description
    TAR DNA binding protein
  • Target synonyms
    ALS10, TDP-43, TAR DNA-binding protein 43, TAR DNA-binding protein-43
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDQ13148
  • Protein Name
    TAR DNA-binding protein 43
  • Scientific Description
    HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Worrall D, Ayoubi R, Fotouhi M, et al. The identification of high-performing antibodies for TDP-43 for use in Western Blot, immunoprecipitation and immunofluorescence. F1000Res. 2023,12:277. doi: 10.12688/f1000research.131852.2
    Read this paper