More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/TDP43 antibody
TDP43 antibody detects TDP43 protein at nucleus by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain. TDP43 stained by TDP43 antibody (GTX114210) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
TDP43 antibody detects TDP43 protein at nucleus by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain. TDP43 stained by TDP43 antibody (GTX114210) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
TDP43 antibody detects TDP43 protein at nucleus by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain. TDP43 stained by TDP43 antibody (GTX114210) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

TDP43 antibody

GTX114210
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTARDBP
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    TDP43 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.63 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID23435
  • Target name
    TARDBP
  • Target description
    TAR DNA binding protein
  • Target synonyms
    ALS10, TDP-43, TAR DNA-binding protein 43, TAR DNA-binding protein-43
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13148
  • Protein Name
    TAR DNA-binding protein 43
  • Scientific Description
    HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Harrell TL, Davido DJ, Bertke AS. Herpes Simplex Virus 1 (HSV-1) Infected Cell Protein 0 (ICP0) Targets of Ubiquitination during Productive Infection of Primary Adult Sensory Neurons. Int J Mol Sci. 2023,24(3). doi: 10.3390/ijms24032931
    Read this paper
  • Chu JF, Majumder P, Chatterjee B, et al. TDP-43 Regulates Coupled Dendritic mRNA Transport-Translation Processes in Co-operation with FMRP and Staufen1. Cell Rep. 2019,29(10):3118-3133.e6. doi: 10.1016/j.celrep.2019.10.061
    Read this paper
  • Wu LS, Cheng WC, Chen CY, et al. Transcriptomopathies of pre- and post-symptomatic frontotemporal dementia-like mice with TDP-43 depletion in forebrain neurons. Acta Neuropathol Commun. 2019,7(1):50. doi: 10.1186/s40478-019-0674-x
    Read this paper
  • Majumder P, Chu JF, Chatterjee B, et al. Co-regulation of mRNA translation by TDP-43 and Fragile X Syndrome protein FMRP. Acta Neuropathol. 2016,132(5):721-738.
    Read this paper
  • Sundararaman B, Zhan L, Blue SM, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016,61(6):903-13. doi: 10.1016/j.molcel.2016.02.012
    Read this paper
  • Huang CC, Bose JK, Majumder P, et al. Metabolism and mis-metabolism of the neuropathological signature protein TDP-43. J Cell Sci. 2014,127(Pt 14):3024-38. doi: 10.1242/jcs.136150
    Read this paper

Datasheet

Download Datasheet

FAQ

Go to our frequently asked questions

Related products

Product group Antibodies
RayBiotech
Anti-TARDBP Antibody144-01183
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, Other Application
ReactivityHuman, Mouse, Rat
TargetTARDBP
  • SizePrice
Product group Antibodies
Biosynth
TARDBP antibody10R-1095
  • SizePrice
Western blot analysis of TDP-43 (GTX100579, upper panel) and beta-actin (GTX109639, lower panel)? Sample (30 ug of whole cell lysate) ? A: HeLa mock control? B: HeLa transfected shTDP-43 10% SDS PAGE? GTX100579 diluted at 1:500
Product group Antibodies
GeneTex
TDP43 antibodyGTX100579
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
ReactivityHuman, Mouse, Rat
TargetTARDBP
  • SizePrice
IHC-P analysis of human prostate cancer using GTX57560 TDP43 antibody. Antigen retrieval: 0.1M sodium citrate buffer Dilution: 1:50
Product group Antibodies
GeneTex
TDP43 antibody [k1B9]GTX57560
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
ReactivityHuman
TargetTARDBP
  • SizePrice
Wild-type (WT) and TARDBP knockout (KO) HAP1 cell extracts (50 Aμg) were separated by gradient gel% SDS-PAGE, and the membrane was blotted with TDP43 antibody [GT225] (GTX630196) diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. Data provided byA?YCharOSA?Inc., an open science company with the mission of characterizing commercially available antibody reagents for all human proteins using knockout technology.
Product group Antibodies
References
GeneTex
TDP43 antibody [GT225]GTX630196
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
ReactivityHuman, Mouse, Rat
TargetTARDBP
  • SizePrice
Wild-type (WT) and TARDBP knockout (KO) HAP1 cell extracts (50 Aμg) were separated by gradient gel% SDS-PAGE, and the membrane was blotted with TDP43 antibody [GT733] (GTX630197) diluted at 1:500. The HRP-conjugated anti-mouse IgG antibody (GTX213111-01) was used to detect the primary antibody. Data provided byA?YCharOSA?Inc., an open science company with the mission of characterizing commercially available antibody reagents for all human proteins using knockout technology.
Product group Antibodies
References
GeneTex
TDP43 antibody [GT733]GTX630197
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
ReactivityHuman, Mouse, Rat
TargetTARDBP
  • SizePrice
TDP43 antibody [GT6310] detects TDP43 Protein expression by immunohistochemical analysis. Sample: Frozen-sectioned adult mouse cerebellum. Green: TDP43 stained by TDP43 antibody [GT6310] (GTX633973) diluted at 1:250. Red: Calbindin, stained by Calbindin antibody (GTX130856) diluted at 1:500. Blue: Fluoroshield with DAPI (GTX30920). Antigen Retrieval: Citrate buffer, pH 6.0, 5 min
Product group Antibodies
GeneTex
TDP43 antibody [GT6310]GTX633973
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
ReactivityHuman, Mouse, Rat
TargetTARDBP
  • SizePrice
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~58k TR-α2 protein using TDP43 antibody (GTX82580).
Product group Antibodies
References
GeneTex
TDP43 antibodyGTX82580
ApplicationsWestern Blot, ImmunoHistoChemistry
ReactivityHuman, Rat
TargetTARDBP
  • SizePrice
Figure 1. Western blot analysis of TDP-43/TARDBP using anti-TDP-43/TARDBP antibody (A01001-3). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sample under reducing conditions. Lane 1: human Hela whole cell lysates, Lane 2: human Jurkat whole cell lysates, Lane 3: human HepG2 whole cell lysates, Lane 4: rat C6 whole cell lysates, Lane 5: mouse pancrease lysates, Lane 6: mouse Neuro-2a whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat milk/TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-TDP-43/TARDBP antigen affinity purified polyclonal antibody (Catalog # A01001-3) at 0.5 microg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:5000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for TDP-43/TARDBP at approximately 43 kDa. The expected band size for TDP-43/TARDBP is at 45 kDa.
Product group Antibodies
Boster Bio
Anti-TDP-43/TARDBP Antibody Picoband(r)A01001-3-CARRIER-FREE
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
ReactivityHuman, Mouse, Rat
TargetTARDBP
  • SizePrice
Product group Antibodies
Biomatik
TARDBP Polyclonal AntibodyCAC14898
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
TargetTARDBP
  • SizePrice