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ProductsBack/Thyroglobulin antibody [5E6]

Thyroglobulin antibody [5E6]

GTX21982
GeneTex
ApplicationsELISA
DownloadDatasheet
Product group Antibodies
TargetTG
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Overview

  • Supplier
    GeneTex
  • Product Name
    Thyroglobulin antibody [5E6]
  • Delivery Days Customer
    9
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Conjugate
    Unconjugated
  • Gene ID7038
  • Target name
    TG
  • Target description
    thyroglobulin
  • Target synonyms
    AITD3; TGN; thyroglobulin
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP01266
  • Protein Name
    Thyroglobulin
  • Scientific Description
    Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

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