Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TNFRSF13C Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TNFRSF13C Polyclonal Antibody at dilution 1:40
TNFRSF13C Polyclonal Antibody
E-AB-16646
Product group Antibodies
Overview
- SupplierElabscience
- Product NameTNFRSF13C Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.7mg/ml
- Scientific DescriptionB cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
- UNSPSC12352203