Transgelin antibody
GTX113561
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse, Rat
TargetTAGLN
Overview
- SupplierGeneTex
- Product NameTransgelin antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.33 mg/ml
- ConjugateUnconjugated
- Gene ID6876
- Target nameTAGLN
- Target descriptiontransgelin
- Target synonymsSM22, SM22-alpha, SMCC, TAGLN1, TGLN, WS3-10, transgelin, 22 kDa actin-binding protein, epididymis secretory sperm binding protein, smooth muscle protein 22-alpha
- HostRabbit
- IsotypeIgG
- Protein IDQ01995
- Protein NameTransgelin
- Scientific DescriptionThe protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
- ReactivityBovine, Human, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Delve E, Co V, Kandel RA. Superficial and deep zone articular chondrocytes exhibit differences in actin polymerization status and actin-associated molecules in vitro. Osteoarthr Cartil Open. 2020,2(3):100071. doi: 10.1016/j.ocarto.2020.100071Read this paper
- Gautam J, Zhang X, Yao Y. The role of pericytic laminin in blood brain barrier integrity maintenance. Sci Rep. 2016,6:36450. doi: 10.1038/srep36450Read this paper
- Parreno J, Raju S, Wu PH, et al. MRTF-A signaling regulates the acquisition of the contractile phenotype in dedifferentiated chondrocytes. Matrix Biol. 2017,62:3-14. doi: 10.1016/j.matbio.2016.10.004Read this paper
- Tang D, Chen Y, He H, et al. Integrated analysis of mRNA, microRNA and protein in systemic lupus erythematosus-specific induced pluripotent stem cells from urine. BMC Genomics. 2016,17:488. doi: 10.1186/s12864-016-2809-9Read this paper
- Yao Y, Norris EH, Mason CE, et al. Laminin regulates PDGFRβ(+) cell stemness and muscle development. Nat Commun. 2016,7:11415. doi: 10.1038/ncomms11415Read this paper
- Levine J, Kwon E, Paez P, et al. Traumatically injured astrocytes release a proteomic signature modulated by STAT3-dependent cell survival. Glia. 2016,64(5):668-94. doi: 10.1002/glia.22953Read this paper
- Gérard N, Chanson-Rollé A, Rock E, et al. Proteomic analysis identifies cytoskeleton-interacting proteins as major downstream targets of altered folate status in the aorta of adult rat. Mol Nutr Food Res. 2014,58(12):2307-19. doi: 10.1002/mnfr.201400317Read this paper
- Yao Y, Chen ZL, Norris EH, et al. Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity. Nat Commun. 2014,5:3413. doi: 10.1038/ncomms4413Read this paper
Datasheet
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