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TSTA3 antibody [C1C3]

GTX101663
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHamster, Human
TargetGFUS
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Overview

  • Supplier
    GeneTex
  • Product Name
    TSTA3 antibody [C1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7264
  • Target name
    GFUS
  • Target description
    GDP-L-fucose synthase
  • Target synonyms
    3-5 epimerase/4-reductase; FX; GDP-4-keto-6-deoxy-D-mannose epimerase-reductase; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; GDP-L-fucose synthase; P35B; red cell NADP(H)-binding protein; SDR4E1; short chain dehydrogenase/reductase family 4E, member 1; testis tissue sperm-binding protein Li 45a; tissue specific transplantation antigen 3; tissue specific transplantation antigen P35B; TSTA3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13630
  • Protein Name
    GDP-L-fucose synthase
  • Scientific Description
    Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II. [provided by RefSeq]
  • Reactivity
    Hamster, Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Generation of FX-/- and Gmds-/- CHOZN host cell lines for the production of afucosylated therapeutic antibodies. Liu W et al., 2021 Jan, Biotechnol Prog
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