Western Blot Positive WB detected in: HepG2 whole cell lysate All lanes: U2AF2 antibody at 2ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 54 kDa Observed band size: 54 kDa
Western Blot Positive WB detected in: HepG2 whole cell lysate All lanes: U2AF2 antibody at 2ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 54 kDa Observed band size: 54 kDa
U2AF2 Antibody
CSB-PA025408LA01HU
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetU2AF2
Overview
- SupplierCusabio
- Product NameU2AF2 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID11338
- Target nameU2AF2
- Target descriptionU2 small nuclear RNA auxiliary factor 2
- Target synonymshU2AF65; splicing factor U2AF 65 kDa subunit; U2 (RNU2) small nuclear RNA auxiliary factor 2; U2 auxiliary factor 65 kDa subunit; U2 small nuclear ribonucleoprotein auxiliary factor (65kD); U2 snRNP auxiliary factor large subunit; U2AF65
- HostRabbit
- IsotypeIgG
- Protein IDP26368
- Protein NameSplicing factor U2AF 65 kDa subunit
- Scientific DescriptionNecessary for the splicing of pre-mRNA. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing (PubMed:21536736). Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203