Western Blot Positive WB detected in: Hela whole cell lysate All lanes: UBA1 antibody at 2microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 118, 114 kDa Observed band size: 118, 114 kDa

UBA1 Antibody

Name: UBA1 Antibody
SKU: CSB-PA00149A0RB_C90
Availability: BackOrder

CSB-PA00149A0RB

ApplicationsImmunoFluorescence, Western Blot, ELISA

Product group Antibodies

TargetUBA1

Overview

Supplier
Cusabio
Product Name
UBA1 Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, Western Blot, ELISA
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID7317
Target name
UBA1
Target description
ubiquitin like modifier activating enzyme 1
Target synonyms
A1S9; A1S9T; A1S9T and BN75 temperature sensitivity complementing; A1ST; AMCX1; CFAP124; GXP1; POC20; POC20 centriolar protein homolog; SMAX2; testicular secretory protein Li 63; UBA1, ubiquitin-activating enzyme E1 homolog A; UBA1A; UBE1; UBE1X; ubiquitin-like modifier-activating enzyme 1; VEXAS
Host
Rabbit
Isotype
IgG
Protein IDP22314
Protein Name
Ubiquitin-like modifier-activating enzyme 1
Scientific Description
Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system (PubMed:1606621, PubMed:1447181). Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP (PubMed:1447181). Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (PubMed:22456334).
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

UBA1 Antibody

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Overview

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