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ProductsBack/VCP antibody [N1N2], N-term

VCP antibody [N1N2], N-term

GTX113030
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityCanine, Human, Mouse, Rat, Zebra Fish
TargetVCP
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Overview

  • Supplier
    GeneTex
  • Product Name
    VCP antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.3 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7415
  • Target name
    VCP
  • Target description
    valosin containing protein
  • Target synonyms
    15S Mg(2+)-ATPase p97 subunit; CDC48; FTDALS6; p97; TER ATPase; TERA; transitional endoplasmic reticulum ATPase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP55072
  • Protein Name
    Transitional endoplasmic reticulum ATPase
  • Scientific Description
    The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. [provided by RefSeq]
  • Reactivity
    Canine, Human, Mouse, Rat, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Protein phosphatase 6 regulates trametinib sensitivity, a mitogen-activated protein kinase kinase (MEK) inhibitor, by regulating MEK1/2-ERK1/2 signaling in canine melanoma cells.
    Read more
  • COMMD3 loss drives invasive breast cancer growth by modulating copper homeostasis.
    Read more
  • FYCO1 Increase and Effect of Arimoclomol-Treatment in Human VCP-Pathology.
    Read more
  • Elevated expression of RAB3B plays important roles in chemoresistance and metastatic potential of hepatoma cells. Tsunedomi R et al., 2022 Mar 11, BMC Cancer
    Read more
  • Protein phosphatase 6 promotes neurite outgrowth by promoting mTORC2 activity in N2a cells. Kitamura N et al., 2021 Sep 22, J Biochem
    Read more
  • Pancreatic Cancer Stem-Like Cells With High Calreticulin Expression Associated With Immune Surveillance. Fujiwara Y et al., 2021 Mar 1, Pancreas
    Read more
  • Protein phosphatase 6 dissociates the Beclin 1/Vps34 complex and inhibits autophagy. Fujiwara N et al., 2021 May 7, Biochem Biophys Res Commun
    Read more
  • Cathepsin B is highly expressed in pancreatic cancer stem-like cells and is associated with patients surgical outcomes. Fujimoto T et al., 2021 Jan, Oncol Lett
    Read more
  • Autophagy regulates levels of tumor suppressor enzyme protein phosphatase 6. Fujiwara N et al., 2020 Dec, Cancer Sci
    Read more
  • Involvement of PP2A methylation in the adipogenic differentiation of bone marrow-derived mesenchymal stem cell. Ikeda S et al., 2020 Dec 26, J Biochem
    Read more