XIAP antibody
![Research Use Only](static/images/certificates/ruo.jpg)
GTX111202
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetXIAP
Overview
- SupplierGeneTex
- Product NameXIAP antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID331
- Target nameXIAP
- Target descriptionX-linked inhibitor of apoptosis
- Target synonymsAPI3; baculoviral IAP repeat-containing protein 4; BIRC4; E3 ubiquitin-protein ligase XIAP; hIAP3; hIAP-3; IAP-3; IAP-like protein 1; ILP1; inhibitor of apoptosis protein 3; MIHA; RING-type E3 ubiquitin transferase XIAP; X-linked IAP; X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase; XLP2
- HostRabbit
- IsotypeIgG
- Protein IDP98170
- Protein NameE3 ubiquitin-protein ligase XIAP
- Scientific DescriptionThe protein encoded by this gene is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. This protein inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. It also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3beta-beta-Catenin and XIAP-Survivin Pathways. Chang YX et al., 2020 Dec 21, Cancers (Basel)Read more
- Pharmacological targeting of HSP90 with 17-AAG induces apoptosis of myogenic cells through activation of the intrinsic pathway. Wagatsuma A et al., 2018 Aug, Mol Cell BiochemRead more
- SP110b Controls Host Immunity and Susceptibility to Tuberculosis. Leu JS et al., 2017 Feb 1, Am J Respir Crit Care MedRead more
- Targeting the XIAP/caspase-7 complex selectively kills caspase-3-deficient malignancies. Lin YF et al., 2013 Sep, J Clin InvestRead more