XPA antibody

GeneTex

XPA antibody [5A2]

9

Western blot: 1:1,000 - 1:1,500 Optimal dilutions/concentrations should be determined by the end user

Dot Blot, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, Other Application

Research Use Only

Monoclonal

0.5 mg/ml

Unconjugated

Liquid

XPA

XPA, DNA damage recognition and repair factor

DNA repair protein complementing XP-A cells; xeroderma pigmentosum group A-complementing protein; xeroderma pigmentosum, complementation group A; XP1; XPAC

Mouse

IgG1

DNA repair protein complementing XP-A cells

This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017]

Human

-20°C or -80°C,2°C to 8°C

12352203