ICC/IF analysis of GM0637 cells irradiated with UV at 20 J/m2 using GTX00704 XPA antibody [5F12]. Dilution : 1:100
![WB analysis of various samples using GTX00704 XPA antibody [5F12]. Lane 1 : HeLa whole cell lysate (XpA wild-type) Lane 2 : XP12ROSV whole cell lysate (XpA deficient) Dilution : 1:2000](https://www.genetex.com/upload/website/prouct_img/normal/GTX00704/GTX00704_20191104_WB_1_w_23053121_993.webp "WB analysis of various samples using GTX00704 XPA antibody [5F12]. Lane 1 : HeLa whole cell lysate (XpA wild-type) Lane 2 : XP12ROSV whole cell lysate (XpA deficient) Dilution : 1:2000")
![WB analysis of HeLa whole cell lysate using GTX00704 XPA antibody [5F12]. Dilution : 1:2000](https://www.genetex.com/upload/website/prouct_img/normal/GTX00704/GTX00704_20191104_WB_w_23053121_985.webp "WB analysis of HeLa whole cell lysate using GTX00704 XPA antibody [5F12]. Dilution : 1:2000")
ICC/IF analysis of GM0637 cells irradiated with UV at 20 J/m2 using GTX00704 XPA antibody [5F12]. Dilution : 1:100
XPA antibody [5F12] - Orthogonal Validated
GTX00704
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetXPA
Overview
- SupplierGeneTex
- Product NameXPA antibody [5F12] - Orthogonal Validated
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID5F12
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID7507
- Target nameXPA
- Target descriptionXPA, DNA damage recognition and repair factor
- Target synonymsDNA repair protein complementing XP-A cells; xeroderma pigmentosum group A-complementing protein; xeroderma pigmentosum, complementation group A; XP1; XPAC
- HostMouse
- IsotypeIgG2b
- Scientific DescriptionThis gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Analysis of a human DNA excision repair gene involved in group A xeroderma pigmentosum and containing a zinc-finger domain. Tanaka K et al., 1990 Nov 1, NatureRead more